The ASPP1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PPP1R13B. This antibody recognizes Human, and Mouse antigen. The ASPP1 Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
Function: Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.
Subunit Structure: Interacts with TP53.
Similarity: The ankyrin repeats and the SH3 domain are required for specific interactions with TP53. Belongs to the ASPP family